NAD+ and cofactors

NAD+ and cofactors, documented lot by lot.

β-NAD+, reduced glutathione, methylcobalamin, methyl folate, alpha lipoic acid and taurine. For NAD+ details, see the NAD+ page.

Sealed white HDPE bottle beside an open glass jar of fine white crystalline powder on a stainless steel bench

NAD+: the regulatory facts

  • β-NAD is in FDA's 503B Category 1, FDA's interim policy for nominated substances it is still evaluating. That is enforcement discretion, not a listing, and FDA can change it.
  • In a Jan 20, 2026 warning letter, FDA told an outsourcing facility that NAD+ was not eligible for the 503B exemptions.
  • The disodium salt trihydrate form of NAD is in Category 3.
  • NAD+ is not on the 503B bulks list or the drug shortage list.

We state these facts, dated, on every quote. Whether and how you use NAD+ is your facility's decision.

What we list (20)

503B Category 1 FDA interim policy, conditions applyCategory 2 FDA safety risk, outside the interim policyBiologic not eligible for 503A/503B compoundingWithdrawn list not for human compoundingNo 503B pathway not on the bulks list, the shortage list or in Category 1503A HHS draft policy formVeterinary animal compounding

Status as of Nov 14, 2026. Sources: FDA 503B categories list (updated Mar 21, 2025), FDA Category 2 page (current Apr 22, 2026), 21 CFR 216.24, 21 CFR 530.41, 21 CFR 600.3(h)(6), HHS FR 2026-22192. No item we list is on the 503B bulks list today. Shortage status is checked when we price your request. Labels are a starting point, not a determination for your facility.

  • β-Nicotinamide Adenine Dinucleotide (β-NAD+) 503B Category 1Price this item

    FDA's Jan 20, 2026 warning letter to an outsourcing facility treated NAD+ as ineligible under 503B. The disodium salt trihydrate form is Category 3. Exact form stated on the quote.

  • 2-Deoxy-D-Glucose 503B Category 1Price this item
  • Alpha Lipoic Acid 503B Category 1Price this item
  • D-Biotin 503B Category 1Price this item
  • L-5-Methyltetrahydrofolate Calcium 503B Category 1Price this item
  • L-Glutathione (Reduced) 503B Category 1Price this item
  • Methylcobalamin (Mecobalamin) 503B Category 1Price this item
  • Taurine 503B Category 1Price this item
  • (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride No 503B pathwayPrice this item
  • 5-Methyltetrahydrofolic Acid (Methyl Folate) No 503B pathwayPrice this item
  • Adenosine 5'-Monophosphate No 503B pathwayPrice this item
  • Adenosine 5'-Monophosphate Disodium Salt No 503B pathwayPrice this item
  • Curcumin 99% No 503B pathwayPrice this item
  • Diindolylmethane No 503B pathwayPrice this item
  • L-Tryptophan No 503B pathwayPrice this item

    503B Category 3 (nominated without adequate support).

  • Leucovorin Calcium No 503B pathwayPrice this item
  • Methylene Blue No 503B pathwayPrice this item

    Not found in FDA’s 503B category list; status to be verified.

  • Resveratrol No 503B pathwayPrice this item

    503B Category 3 (nominated without adequate support).

  • Sirolimus (Rapamycin) No 503B pathwayPrice this item
  • β-Nicotinamide Mononucleotide (NMN) No 503B pathwayPrice this item

    Not found in FDA’s 503B category list; status to be verified.

Questions

Which NAD+ form do you supply?

β-nicotinamide adenine dinucleotide (β-NAD+). The exact form comes with the quote.

Do you carry glutathione for injection lines?

Reduced L-glutathione is on the list (503B Category 1). Mark the request for sterile use and ask for endotoxin data.

What comes with the quote?

A price and pack size per item, the lot COA and the item's dated status.

Every quote includes

A written price and pack size per item, the lot COA, and each item's FDA status as of the date we price it. Nothing ships until you approve the price sheet.

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